Personnel Management And Human Resource Management Commerce Essay

military force trouble And humanity Resource Management line of business EssayAs per the senior counselings comment in the meeting Our Comp both(prenominal) is suffering in the marketplace, as we beat a person-to-person counsel shape up rather than a HRM approach.Report to answer Managers query This report has been designed in order to enable the line music director to address the issue raise in the solicitude meeting. What we read from the managements comments is that our new stick in of TESCO Company is veneering lot of issues and competition at the new market place.Similarities and differences between HRM and personal management?Why senior management of TESCO feels that our new shop class should eat up a HRM approach instead of a personal management approach?Personnel management expands into human imaginativeness management. In general terms, Personnel management is considered to be an administrative run away of an organization. Personnel management is suppos ed to be organized in such a way that any changes in the organisation stimulate response from military unit management.In an organisation, a person or a aggroup of individuals ar believed to be engaged in the process of Personnel management, when they become in charge of considering programs and making certain denounceting policies are appropriately set so that it can have an equal on every individual associated with the smart set and its military operation.Objective of military unit Management By this we mean that the focus efflorescence through which personnel management is helping in development of the the great unwashed in the organisation. These objectives can be divided in 4 typescommunityPersonnelProjectAmalgamationWhat is an excellent personnel management Char impresseristics of personnel management when it is considered to be excellent has been listed on a lower floorPersonnel management is expected to bring stabilityPersonnel management should be adaptable and c apable to encounter any issueEmployee relation managementShould have a set objective for the surgical incision or the organizationFunctions of Personnel Management Following are some of the functions of Personnel ManagementAssessing employees requirementHiring employeesScreening of the appliersSelecting the applicantsOrientation of the new hired employees towards rail line1. 1 Definition of Human Resource Management (HRM)?As per Human resource management, employees are considered the well-nigh valuable assets of an organisation. HRM is considered as a development function of an organization.Objectives of Human resource management Management of the manpower in any ac smart set or organisation is human resource management. The main objective of HRM is to add the efficiency and performance of the employees, mental faculty and other de single outment by identifying the job requirements and hiring the appropriate scene for that post. This has both development and implementation of strategy.What is good human resource management HRM is considered to be resource centered. The main functions of HRM are listed below,Recruiting employeesDevelopment of training programs carrying out of trusted appraisal systemProvide growth chance in organisationPerformance managementHR planningEmployee retentionImplementation of new resources to increase efficiency of employee etc1.3 Similarities and differences between HRM and personnel managementIn this part we depart cover some of the similarities and differences between Personnel management and Human resource management.Similarity between HRM and Personnel Management Even though most of the people try to evaluate the difference between HRM and Personnel management, at that place are lots of the similarities between these two management systemsBoth graze on business based strategiesBoth HRM and Personnel management understands the responsibility of a managerBoth believe is getting right candidate for right jobBoth understa nd that interaction with employees is the key for the success of managementDifferences between HRM and personnel management Stephen and Keith in their works mention Storey Js (1992 twenty septette points of difference between Personnel management and HRM, of which some key differences are27 points of differenceDimensionPersonnelStrategic aspectsKey relations wear upon managementInitiativesPiecemealSpeed of excisionSlowLine ManagementManagementTransactionalKey managersPersonnel/ IR specialistsCommunicationIndirectKey levers pickingSeparate, marginal taskPayJob evaluationCommunicationRestricted flowConflict discourseReach temporary trucesHRM is more proactive when compared to personnel managementPersonnel management is in general operational whereas HRM is strategy basedPersonnel management focuses in workforce whereas Human resource on resource.As per personnel management employee is supposed to be utilized for companys benefits but in human resource management, not only the compan y but alike the employee, their family should be given the benefits.In personnel management, employee is considered to be the cost center, whereas in human resource management, they are considered as profit centersFunctionPersonnel ManagementHRMApproachAdministrativeDevelopmentSelectionTargets the current needsTargets the trainability and retentionDeploymentNeed basedSkill basedPerformance ReviewSupervisor orientPre defined targets and goals. Aims for transparencyPromotionsBased on performance and needPre developed career path1.4 Why Senior management TESCO feels that our new store should scram a HRM approach instead of a personal management approach?Comments say that our company is suffering in the marketplace, as we take a personal management approach rather than a HRM approach.At first when we go through the senior managements comments, we dont see any details regarding the reason which has provoked the management to pass this comment. Even though we can clear understand that there is a serious issue that our new store or company is facing in the marketplace.As mentioned earlier reason for the poor performance has not been highlighted in the comment. Based on our assumption we can consider the problems related to round turnover, customer handling, job satisfaction, etc. The other reason can be that the customers coming to the store are getting poor service and minimal precaution to their needs. So based on this we can consider the issue to be the employee management.We know that if the staff performance is not up to the mark, it has a direct impact on the status of the TESCO Company and their other stores as well. The senior management might having the opinion that since this a new store with lots of challenging spot, it needed development work. As per the managements comment, we can understand that if we want our store to be successful in the marketplace, we need to start on the job(p) based on Human resource management.Task 2. Recruitment, selecti on and retention (L01)We all know that TESCO has both food and non-food store across United Kingdom, and they keep on recruiting staff extremitys on regular basis for these stores as per the requirement. Use of appropriate hiring and selection process not only saves valuable amount of judgment of conviction as well as cash of the company. Any job position becomes available in a companyOpening of new storesVacanciesSudden requirement at some store2.1.1 Recruitment and Selection ProceduresUsually we will see people getting confused with the terms recruitment and selection. In this section we will clearly rationalize the difference between Recruitment and Selection process. The HR process has two stagesRecruitment The process of finding the correct candidates and encouraging them to apply for jobs vacancies in the company is called Recruitment process. Recruitment process involves seven stepsJob vacancies identificationPreparing and consolidating specific job requirementJob adverti singManaging the responses received through the advertisementShort-listing the candidatesArranging interviews for the short-listed candidatesConducting interview and deciding on the right applicant in that respect are two methods through which recruitment of an employee can be done inside recruitment Internal recruitment is nothing but Transfers, promotions and Re- work of ex-employee. This is performed internally in a companyExternal recruitment In this people are invited to assemble in the job application and attend interview. This is outside the company means all the appropriate candidates can apply for the job posting.Recruitment mainly helps company in 4 diametric waysOpting for highly qualified people for the jobMaking sure candidate stick for long time with the companyCreating cultural mixtureExpense and profit equalizingSelection Selection is the process of selecting the right candidate out of all the picked candidates. This process involves lot of phases through which an applicant goes through before selection. This is a critical step as in this process the right applicants is selected as per the job opening available in the company.There are four likely out comes of Selection processSelection of the right applicant (positive for company)Rejection of unsuitable applicant (positive for company)Selection of reject-able applicant (negative for company)Rejection of appropriate candidate (negative for company)Selection process takes place in the following orderInitial interviewApplication fillingVerbal and written testInterview with HR managerHandover of Appointment letter2.1.2 Tescos Recruitment and selection processTESCO- The biggest private sector employer in United KingdomThere are lot of people who are part of these stores and they are Checkout staffs, Stock handlers, Supervisors and specialist like bakers, pharmacist etc.The Recruitment process in TESCO can be summarized as followsAs Tesco recruitment is mainly done through there website or through job advertisement regarding the vacancies available at the store.This site contains all the schooling about the company and the requirements for the particular job vacancy.Usually TESCO site is uploaded with all the job vacancies and the candidates just need to search the appropriate job by victimization search option.One the application is filled, the candidate is called for interview based on screening.Any company first checks on the list of the current employees at different stores and there past work experience at store.As per qualification, education and earlier job experiences, initially the candidates will be filtered.Line manager will make sure suitable candidate is selected for our new store.2.2.3 Sample interview questionnaire beneath are some of the questions asked in interviewsWhy do you want to critical point TESCO?What are reasons for you to leave your previous job?Tell us something about your strengths?What do you consider as your weakness?Are you good at handlin g work related pressure and stress?What salary expectation you have?Tell us something about yourself?What is your qualification?Tell us something about your previous experiences?What are your expectations from Managers and Team leaders?2.2 RetentionEmployees or the staff members are like the back bone for company. No company can work without staff skillful staff members. Commonly employee dissatisfaction leads to resignation, hence as far as employee satisfaction is concerned being manager of a new store, the responsibility is to hit not only customer satisfaction but also as employees satisfaction.Employee Retention is created by Effective Managers. As recruiting a skillful staff member is difficult same way retaining them is lot more challenging. Employesses in any company expect compensation, good working environment, career growth and good working relationship. Employees tend to leave managers who cantClarify issuesAssist in career growthGive regular performance based feedbackO ne way of guardianship your cost down will be to make sure that staff turnover is low.2.2.1 Why module leaves the job?In this section we will take a look at some of the reasons that provoke an employee to leave their current jobNew job Every person looks out for better opportunity if they are not finding one their current job.Higher Salaries This is most common reason for any staff member to leave the job unequal managementHuman Resources department response to employeesCommunicationWork environmentJob satisfactionNo growthBiased2.2.2 Method to retain the Staff membersFollowing are some of the suggestion to increase Staff retentionRecruit people who have talent, ability and ready to work in any positionProvide benefits like life insurance, permanent or temporary disability insurance and flexible hours.Regular feedback session based on performanceGrowth opportunityCelebration at workplaceProper appraisal systemRegular appreciationGood work environmentShould provide work and life ba lance opportunityRegularly address is staff issues2.3 Legal and Ethical Issues in RecruitmentRecruitment process is not simple as it sounds. Lot of heavy and ethical issues needs to be kept in mind during this process. To meet sound requirement company needs to make sure that Job postings, inspecting references, interview questionnaire, and job offers all need to be done in appropriate way. As per BC Human Rights Code (Discrimination in employment advertisements), a job should not be published if it gives preference to the followingRace/CastColorHeritagePlace of originReligious sentenceMarital categoryBelief involving politicsFamily statusAgePsychological disabilityPhysicalReligious convictionAny applicant can take legal action against the company if the question is in appropriate. In order to keep the staff members aware of the legal and ethical issue pertaining to company, the store manager can provide a handbook once the candidate is selected.An employer should always be ready with the appropriate documents supporting that the job requirements are legal and not against the ethics of the company.3. Disciplinary Procedures3.1 IntroductionThe main focus of implementation of disciplinary process is to bring out improvement in an employee or staff member.Implementation of Disciplinary procedure is very important in any work place. A staff member needs to be aware that when ever there is something going wrong, it was an end result. Whenever any employee breaks policies of the company or doesnt work to their expectation, disciplinary procedures is administered. Usually disciplinary procedure is applied when a staff members performance is below expectation or not up to the mark. Before an appropriate action can be taken disciplinary procedure demands an explanation of the issue from both the sides. There are two ways of handling these situations In musket ball and formal. An informal step involves talking to the staff personally and internally but a formal step i nvolves other departments like HRM. There are different methods in application of discipline like Warning (verbal or written), Probation, Suspension/ transfer, Demotion, DischargeBelow mentioned the issues that have been observed recently in the Store will give a clear understanding about disciplinary procedure3.2 Paul Wilkinson attack late and go away earlyIssue Paul Wilkinson a 44 year old supervisor has recently been coming to work late and leaving early. You have already spoken to him about this, but unfortunately the situation hasnt improved.In this case,Supervisor is expected to be extremely punctual as they act as role models for the new staff.As this is a ingeminate offence from Pauls side, initially he was given verbal warning but as the situation has not improved, he will be given a written warning.Try to speak to him and offer him some other shift in which he can work with commitment without compromising on the time.Putting him on probation can also a an option.Transf erring him another store is just waste of time and cash. It will only hamper other stores performance and reputation as well.Depending on seriousness of the offense, next time can lead in his demotion or removal from the job.To better understand Pauls recent activity, we need to know ifHe is facing any family or personal issue pertaining to time of work.Is he no longer happy working at the storeReason for his dissatisfaction if any3.3 Sheena Johnson Stealing in the StoreIssue Sheena Johnson is 28 and a machine factor in the department. You have been informed that security found her stealing some finished and part-finished items from the department. She has been told to report to you at 9 a.m. tomorrow morning.In this caseIn Sheenas case, legal action is necessary to be taken to handle this issue.In any industry or organization stealing is against the ethics of the store and legal action can be taken depending on the seriousness of the offence.Being a manager, I need to make sure t hat this offence is not repeated either by Sheena or anyone else.If this information becomes public, customer will not come into the store as they wont find their articles safe.Before taking legal actions, immediate terminate Sheena from her post and clear the accounts. Order her to return back all the articles stolen from the shop or pay compensation.Other information needed to understand Sheenas activity isFrom when she has started stealingPossible reason behind this act4. SummaryManagement is getting all different kinds of people together and work as a team. We know that the management of personnel and human resource has been changing periodically. Stability in business is important and human resource management and personnel management has an important role to play.Through the above task we have got a clear understanding of how personnel management differs from human resource management as well as similar to each other. Through the report development, we will help the line manag er to address the issue pertaining to the new store at the market place. We have discussed how Tesco has been of selecting right candidate through appropriate recruitment and selection process. We discussed about the reasons for the staff members to leave the job and the retention methods that are implemented to retain the skillful employees.

Computational Design and Management in Pharmaceuticals

computational Design and Management in PharmaceuticalsComputational design and management in pharmaceuticalsLiu SuiAbstract byout the years since the calculating machine was first developed, the estimator has become required and indispensable in sensory systemrn participation. Signifi tail assemblyt scientific usage of computers has spread throughout every the sciences, including pharmaceutical science. In pharmaceuticals, usage has become an essential tool for the whole medicine development process, from initiation of lead searching to determination the best fit, to examineing toxicity. This paper exit give an overview on how computers ar utilize in the field of computational drug design.The development of computers is a short exactly enkindle history. Looking back at this short history, it perfectly illustrates the intelligence and grittiness of mankind. Since the invention of electronic intelligence, this industry has been growing at an amazing pace. From the techni cal point of view, computers gain changed a huge amount since ENIAC in 1946 to the modern day Intel and ARM architectures permeating our life (Bellis). Computers ache changed their role from supercomputer being used for big companies and organizations to the individualized computer that exists in just well-nigh every household, in one way or a nonher. IT companies have also changed from marketing huge computers to marketing tiny computers to be used in the household, that synchronize with the fast rushs of the modern internet. In 1946, ENIAC was co-operated by the U.S. government and the University of Pennsylvania department of computer science (Goldstine). Features of this first coevals of computers were that operating instructions were prep atomic number 18d for a specific task, and each machine had its own dissimilar mechanical languages. This generation of computers had very limited functionality and dimmed touch on speed. Nonetheless, in less than 60 years, computers h ave become tools that are used by some(prenominal) different fields of study to enhance their overall value.The rapid development of computer technology has led to a massive expansion of computer- connect applications in the pharmaceutical industry. From the local computer system-based assistance, to the inevitable development of net manoeuvre-based assistance, usage of computer networks has become an inevitable trend. Both the computer industry and the pharmaceutical industry influence each other, and the combination of penetration, has and will continue to impact the operating mode of chemists shop. Management and technical decisions made today at heart the pharmaceutical industry trick be combined with the development of computer technology. All pharmacy workers should be aware of this and both future developments. In recent decades, due to the application of computers in pharmaceutical technology, m either important achievements have been achieved.Since antiquity, humans h ave build many tools to physically extend their physical capabilities such as the wheel, the pulley, and the vehicle. On comparison, creating devices to extending mental capability, such as the abacus, calculator, and computer, has also been a great human achievement. Computers are unlike any other tools in which they brush off replace human labor under pre-programed condition for an indefinite duration. An item solo becomes profitable for society depending on its function, where computers have many unique features to take up them ideal for society Computers have incredible calculation ability. Computers have a huge memory, in recite to go through macro data setsThe CPU and GPU of a computer have the ability to carry out billions of complicated math operations per second. In footing of the pharmaceutical technology industry, this huge processing speed is vital for the complex mathematical operations required of this emerging discipline, such as calculating pharmacy financ es, calculation and maintaining of pharmaceutical inventory, all the way to calculating drug and other protein formulas, determining the computational drug metabolism and its cogitate pharmacokinetics computing, and pharmaceutical pattern actualisation. many an(prenominal) computer-based programs have been developed and continue being improved to fill the huge directs of this industry. In the developmental stage of drug design, to search for drugs that possess the final energy in chemical structure post take a very long time, and is hard to do. Many people may question wherefore do we need to calculate the lost energy possibility structure, and this question cannot be answered in one simple sentence.In chemistry, each element is big(a) a symbol. Molecular formulas use these elemental symbols to show substantive (whether its an element or a molecular compound) composition of molecules and their relative molecular weight. chemical formulas are liberally used to present chem icals and chemical reaction. In nature, many drugs have different chemical formula, tho at the same time, some compounds that have the exact same molecular formula may not be the same compounds these compounds are called isomers. Isomers have same chemical formula but different atomic arrangement, and the cause of isomers is the change of order between atoms or groups. One type of isomers is called constitutional isomer. For example, ethanol and methoxymethane both have the chemical formula of C2H6O, but ethanol has an alcohol group, and methoxymethane has an ether function group (figure 1) Figure 1 chemical formula of ethanol and methoxymethane. This is where the software, Gaussian, becomes an invaluable part of pharmaceutical chemistry. Gaussian and its connect software, Gaussview, are used to search for conformation amongst molecules. Stereoisomers have the molecular atom and group connected to each other in the same order but have different spatial arrangements. Many people m ay ask why we should care about the spatial arrangements. To answer this question, we need to think about molecules in terms of Classical Physics versus Quantum Physics. In chemistry, each chemical bond contains potential energy. The higher energy level the compounds bonds at, the less stable the compounds becomes. To make a more stable compound is a goal for many chemists because stable compounds have less of a chance to be decomposed, and in nature, many natural products being produced are those in their lowest energy states. The Classical Mechanics approach is mainly used for study of macroscopic objects in slow to stationary motion. Through studying the measureable movements through experiments, chemicals optimal nuclear positions can be found, and the lowest energy state can be found through graphing. However, in chemistry, all chemical bonds are in constant vibration and the ability to study the energy state of electron distribution is more useful for finding the lowest feasi ble energy state. The optimal distribution of electron can be done by quantum mechanics. To think of energy as waves in the ocean, the lowest possible position is actually quite hard to find. It is possible to find some bumps, but these might not be the lowest points. To find the lowest energy points, huge amounts of calculation are needed. At this point, computers become essential. By inputting atomic coordinates, model chemistry and basis set into the software, Gaussian, the software will do the rest of the calculations and provide correct output including atomic coordinates, energy, and a wave function. The wave function can be further interpreted into molecular orbitals, partial charges, electrostatic potential surface, chemical shifts, bond orders, and spin densities. In order to find all these information, a high degree of the true is required. However, computers completely have a certain amount of accuracy they can solo simulate continuous functions and numbers up to a fin ite point, leading to an accuracy problem. In general, most chemistry calculations have a certain degree of error that is allowed as long as the relative error in within the sufficient acceptable error range. Theoretically, the precision of calculation by computer is unlimited, but in practicality, most only go as far as a certain amount.Beyond building a drug at its lowest energy state, or find a drugs certain conformation with incredible speed and accuracy, the huge data storage and memory capacity allow for huge amounts of library research. There are huge online drug repositories (both public and private) for researchers and scientists to search for their targeted drug. During the drug development phase, the first part of any research is to screen for lead compounds and modify these lead compounds to make them work on human biology. Because there are literally millions of compounds available to start from, how should one most efficiently find the compound desired? The answer is through computational lead compound search. Computers will input parameters given and search for lead compounds that fit the requirements and list them out with more information. Information retrieval of drug related data is an essential tool in the pharmacists tool belt.One example of a great computational research tool used for computational design of drugs is the OpenEye OMEGA software suite. OMEGA is the name of a software product belonging to the OpenEye scientific software suite. OMEGA is a stiff tool for cover version toxic chemical groups and providing validation of Lipinskis rule of 5. OMEGA and vRocs have large libraries that can provide much help throughout the usage of computer-aided drug design. The OpenEye product claims that it performs rapid conformational expansion of drug-like molecules, yielding a throughput of tens of thousands of compounds per day per processor (open eye website). This is a huge search, and without the modern memory, data storage, and speed of modern computers, this task would be impossible. At the beginning of any computational research, researchers have to get into a specific mindset. First, what disease does this researcher want to work on? Based on the disease selected, what drugs are currently on the market? Third, are there any other drugs can be any possible new drug candidates? At this point, researchers can start putting their desired pharmacophora into a computer, and let the computer search the library to suggest any possible candidates for further research.Automated drug screening is a good example of this type of raw processing speed and breadth of data to go through. Extensive automatic pharmacological screening for compounds is the traditional and effective method to find new drugs. The sources of compounds are available for screening on a wide range of values including synthetic compounds, natural extracts, microbial fermentation, and compounds obtained by combinatorial chemistry techniques. There are a l arge number of these compounds possible, so in order to avoid leakage of data across screenings, screening needs to go through a few dozen general pharmacological screening models. To have the best possible outcomes, usually the combination of computer and robates for a netter system can run a screen quickly, efficiently, and on a large scale of samples. Currently, 10g of a typical compound is a sufficient amount to go through dozens of pharmacological screenings, and as tens of thousands of compounds can be screened per day, this provides valuable research and development of lead compounds.Within the past few years, even the regular computer is able to store a lurch amount of information. In order to perform the screening methods mentioned above, computers need to have large libraries. However, having a large library is not enough for computer to perform computational research a certain amount of AI logic is also required. This AI logic ability as implemented through archetype ca usality digest is the ability to analyze the proposition being established in order to make the appropriate countermeasures. This logic, or pattern recognition, is nowadays intimately implemented by computers. OMEGA is one program can be used for pattern recognition.Drugs are used to cure diseases, but for many drugs, they can be toxic to human at the same time as they are helping us control and cure some diseases. Pattern recognition uses the computer using mathematical methods to study automatic processing techniques and interpretation models. We consider the environment and objects within as a model. With the development of computer technology, it is possible to model extremely complex human information processing. An important form of this type of modeling is the identification process on the environment and the living embody object. OMEGA can take as input information on the compounds generated by Gaussian and run through GaussView to separate out out toxic compounds. This filter can recognize extremely complex pattern. In this filter, many structures are programed in as toxic groups. Any compounds possessing properties of any of these toxic groups will not pass this filter. Other than toxic groups, this program can also recognize number of hydrogen bond donors (HBD) and hydrogen bond acceptors (HBA). HBD and HBA counts are important for drugs because they are important indication for if a drug candidate can be a production drug or not. Dr. Lipinski is the scientist who first comes up with a alleged(prenominal) rule of five. Linpinskis rule of five was created in 1997 after Christopher A. Lipinski studied 2245 drugs appear on the World Drug Index that have passed phase II clinical trials. By study these drugs structural features he came up with four rulesThe molecule weight of these compounds less than 500.The number of HBD is less than 5.The number of HBA is less than 10.logarithm P is less than 5 (Lipinski) (Lipinski et al)Because of Lipinskis study , the number of HBA and HBD become one critical point when dealing with finding new drug candidates. The variable P is the lipo-hydro partition coefficient, and Log (P) is used to measure the solubility comparison of a compounds solubility of octane to water. In order to pass through the body, drugs need to be polar in order to dissolve in the bloodstream. However, a drug should not be too polar, because it needs lipophilicity to pass through kiosk membrane. OMEGA is able to filter all these individual factors, and provide the end user a spreadsheet with all the information contained.After initial candidates search, it is time to trial if the drug has a good binding to the target protein. In the human body, drugs need to bind to target protein thereby either inhibit or conjure up a series of biological reactions. How well a drug can bind to its target directly affect this drugs efficiency. This structure-activity relationship is related to a drugs pharmacokinetics and pharmacodyn amics. The chemical structure affects a drugs properties, and these structures will decide which protein this drug will interact with. A drug should not be too tightly bound to the protein because in this case the drug will be very hard to be metabolized and eliminated through the body, and can cause accumulation in the body, and be toxic. To measure how well a drug can bind to its target, the software VIDA is the best choice. VIDA is a program which can visualize docking results of the drug with the protein in a 3D view.Beyond this entire skillset of detailed programs within pharmaceutical chemistry, it is also nice to have a computer that is easy to use, able to perform automatic work, and bind all these programs together. As more and more modern drug analysis use computer instruments for analysis, so many different analytical instruments and computer connection and so many different instrumentation and automation for online use are not only for the determination of electrochemica l, spectroscopic, kinetic equilibrium constant, but they are also used for data processing, statistical analysis and results. This all will allow for drug analysis continue to move forward in a sensitive, accurate and rapid direction.Over the years, computer has been developing rapidly, and at the point, people are not only working on making computer faster. Instead, people trying to put this powerful Programs are designed for people, and by people, reflecting the peoples way of thinking and behavior of action, mobilise to replace part of the program and will be able to simulate human thinking and activities.ReferenceBellis, Mary. The History of the ENIAC Computer. About.com Inventors. About.com, 16 May 2014. Web. 03 June 2014.GOLDSTINE, HERMAN H. Computers at the University of Pennsylvanias Moore School, 1943-1946. Computers at the University of Pennsylvanias Moore School, 1943-1946. PROCEEDINGS OF THE AMERICAN PHILOSOPHICAL SOCIETY, 1992. Web. 04 June 2014.Lipinski, Christopher A . Lead- and Drug-like Compounds The Rule-of-five Revolution. Lead- and Drug-like Compounds The Rule-of-five Revolution. Elsevier B.V., Dec. 2004. Web. 04 June 2014.Lipinski, Christopher A., FRANCO Lambardo, Beryl W. Dominy, and Paul J. Feeney. Experimental and Computational Approaches to Estimate Solubility and Permeability in Drug Discovery and Development Settings. Experimental and Computational Approaches to Estimate Solubility and Permeability in Drug Discovery and Development Settings. Elsevier B.V., Mar. 2001. Web. 04 June 2014.1

I Am Proud of Who I Am Essay -- Personal Reflection Essays

Ralph Waldo Emerson once said To be yourself in a world that is nerve-wracking to make you something else is a great accomplishment. Who am I? is question that some(prenominal) often struggle to answer, besides for me it allows me to differentiate from my constituents and express who I real am. What makes me such a unique individual is my ability to identify with 5 strong specialisations. I love the detail that I am futuristic and I piss the ability to relate, I am responsible, I am a developer and last but non least(prenominal) I am disciplined. Each whiz these themes shape and generate my personality. Born on February 22nd 2000 I am the only daughter to Rob and Theresa J anes. When Im not roaming the illustrious campus of say University, I enjoy shopping I personally feel retail therapy is the best therapy I love expending succession with my family they understand me when know one else does, traveling to tropical islands, cooking, going to church and pampering my toy poodle Chanel Briana. When we argon born, most of us are given a suitcase fully of standards, acceptable behavior, things to learn, values & a whole load of dos and donts. As we grow and occur in life we keep adding or throwing away some contents of this suitcase. Each of us thus becomes a product of the choices we have made or that we have consciously decided not to make. Since childhood, we have our dreams and we want to make them a reality. Part of these dreams is ab expose what we become and that results in the career we choose. My ultimate erotic love in life is to impact the lives of many in the healthcare field this also lead my decision in choosing public health as a career choice. By thinking in advance for the future it brings out my futuristic strength. By nature, I channel my mental and physical energies to... ...iod when it comes to paying bills, arriving on time to work or simply having bluff communication with someone those are all characteristics of responsibi lity. One distinguishing personality trait that makes me exceptional is outgoing personality. This is paired with my developer strength and my inability to connect with people. I have the capability to see the potential in others. In my circle of friends I have became the confidant and the one the vociferation for advice, this also balances my developer trait because others seek me out for help and encouragement given on some level they know that my helpfulness is both genuine and fulfilling. Im compassionate about the winner of my family and friends and the ones that truly care for me. Having a positive attitude and spreading a big smile is an act of almsgiving that I try to exhibit with the daily roles I play in life. I Am Proud of Who I Am Essay -- Personal Reflection EssaysRalph Waldo Emerson once said To be yourself in a world that is trying to make you something else is a great accomplishment. Who am I? is question that many often struggle to answer, but for me it allows me to differentiate from my constituents and express who I really am. What makes me such a unique individual is my ability to identify with 5 strong strengths. I love the fact that I am futuristic and I have the ability to relate, I am responsible, I am a developer and last but not least I am disciplined. Each one these themes shape and generate my personality. Born on February 22nd 2000 I am the only daughter to Rob and Theresa Jones. When Im not roaming the illustrious campus of State University, I enjoy shopping I personally feel retail therapy is the best therapy I love spending time with my family they understand me when know one else does, traveling to tropical islands, cooking, going to church and pampering my toy poodle Chanel Briana. When we are born, most of us are given a suitcase full of standards, acceptable behavior, things to learn, values & a whole load of dos and donts. As we grow and progress in life we keep adding or throwing away some contents of this suitcase. Each of us thus becomes a product of the choices we have made or that we have consciously decided not to make. Since childhood, we have our dreams and we want to make them a reality. Part of these dreams is about what we become and that results in the career we choose. My ultimate passion in life is to impact the lives of many in the healthcare field this also lead my decision in choosing public health as a career choice. By thinking ahead for the future it brings out my futuristic strength. By nature, I channel my mental and physical energies to... ...iod when it comes to paying bills, arriving on time to work or simply having open communication with someone those are all characteristics of responsibility. One distinguishing personality trait that makes me exceptional is outgoing personality. This is paired with my developer strength and my inability to connect with people. I have the capability to see the potential in others. In my circle of friends I have became t he confidant and the one the call for advice, this also balances my developer trait because others seek me out for help and encouragement given on some level they know that my helpfulness is both genuine and fulfilling. Im compassionate about the success of my family and friends and the ones that truly care for me. Having a positive attitude and spreading a big smile is an act of kindness that I try to exhibit through the daily roles I play in life.

The Fight for Human Rights Essay -- the security-for-rights compromise

Can you imagine a life without pre-meditated murder? In his movie nonage Report, Steven Spielberg brings this vision to humanity in the trappings of a police state. The pre-crime unit is charged with the elimination of pre-meditated murder using three pre-cogs, humans with the ability to predict violent crime. Minority reports- sporadic, erroneous predictions- indicate the fallibility of this system of imperfect procedural justice. Civilians have their rights to privacy violated on a regular basis for collection of intelligence. This movie is chillingly liable(p) in the real world, as today African-Americans and Muslim-Americans have their rights violated regularly in the name of security.Thankfully, we have more than a Hollywood protagonist to compete for the protection of rights. John Stuart Mill, Robert Nozick, and John Rawls volunteer a philosophic framework for evaluating the security-for-rights compromise. Though their respective theories vary greatly in theory and in pract ice, they provide models to condemn this exchange. Nevertheless, each differs in the persuasiveness and effectiveness of their tools for argumentation. Mills utilitarianism, Nozicks libertarianism, and Rawls egalitarian liberalism reject the tradeoff of security for a majority in exchange for the violation of the rights a minority. John Stuart Mill outlines a sometimes dubious plan for protecting rights and lacks the a priori protection of rights that Rawls and Nozick afford. John Rawls presents the most convincing and solid argument for the omnipotence of rights in the confines of a welfare state. His philosophy acts as an ideal synthesis of libertarianism and utilitarianism he demands the utmost respect for rights while seek to maximize utility f... ...t for rights because tom turkey Cruise says so and because Mill, Nozick and Rawls prescribe it. Works CitedBentham, Jeremy. Introduction to the Principles of Morals and Legislation. Published online by Constitution Society. Web 18 June 2015.http//www.econlib.org/ subroutine library/Bentham/bnthPML.htmlMill, John Stuart. Utilitarianism. Web 20 June 2015.http//www.utilitarianism.com/jsmill.htmNozick, Robert. Distributive Justice. Macquarie University, Modern Political Theory. Web 18 June 2015.http//www.csudh.edu/dearhabermas/nozick01bk.htmlRachels, James. The Elements of Moral Philosophy. Birmingham, Alabama Mcgraw-Hill College, 1999.Rawls, John. A Theory of Justice. Harvard, MA Harvard University Press, 1999.Minority Report. Dir. Steven Spielberg. Perf. Tom Cruise, Max Von Sydow, Steve Harris. Videocassette. 20th Century Fox, 2002.

Drowsy Driving: A Health Promotion Teaching Tool Proposal Essay

Drowsy tearaway(a) A Health Promotion Teaching Tool Proposal This paper is a end for a health promotion teaching tool to raise awareness of the dangers of drowsy driving and to provide some tips and hints to help people reduce their adventure and increase their safety while driving. The target audience is primarily the status post motor vehicle accident patient recovering as an con on the medical/surgical unit of New London Hospital. However, there may be a useful spill-over effect and this tool could also be used by families and visitors to the Medical Surgical unit. The tool would be available on the medical/surgical unit of the hospital in the form of a tri-fold color pamphlet, placed in a hallway between the patient rooms and the rehabilitation gym. The expected outcome is that after picking up and nurture the tool, patients would be more aware of the risks and hazards of drowsy driving and make choices to reduce their risk and increase their personal safety when d riving. DROWSY DRIVING In the preceding(a) several decades, our society has grown from a one for the road attitude to a zero tolerance approach to driving while intoxicated. A dissipated look at the evening news shows us that many different states considering measures to prevent texting while driving, and distracted driving is now a phase in common use. We understand the dangers of driving under the influence, texting while driving and distracted driving however, drowsy driving continues to be a problem on our roads. take assessment Between 1998 and 2008, 16.5% of fatal car accidents in the US involved a drowsy driver, and 13% of non-fatal accidents where at least one person was admitted to the hospital involved a drowsy d... ... the American Medical Association .1998 279(23)1908-1913. doi10.1001/jama.279.23.1908.Microsoft. (2014) Test Your Documents Readability. Retrieved from http//office.microsoft.com/en-us/word-help/test-your-document-s-readability-HP0101485 06.aspxBM2National Highway Safety and Traffic Administration (n.d.) Drowsy Driving and Automobile Crashes. Retrieved from http//www.nhtsa.gov/people/injury/drowsy_driving1/drowsy.htmlTefft, B., (2012). Prevalence of Motor Vehicle Crashes Involving Drowsy Drivers, United States, 1999-2008. Accident Analysis and Prevention. 45(2012) 180-186. http//dx.doi.org.ezproxy.snhu.edu/10.1016/j.aap.2011.05.028U.S. Department of Health and Human Services. (2013). Healthy populate 2020 Initiatives Injury and violence prevention. Retrieved from http//www.healthypeople.gov/2020/topicsobjectives2020/objectiveslist.aspx?topicId=24

Chromatography Essay examples -- essays research papers

Chromatography is a separation technique in which the change to be isolated is dissolved in a solvent and the resulting solution, often called the mobile phase, is then passed through or over an new(prenominal) material, the stationary phase. The separation of the original mixture depends on how strongly each component is attracted to the stationary phase. Substances that are attracted strongly to the stationary phase will be retarded and not move only with the mobile phase. Weakly attracted substances will move more rapidly with the mobile phase.Liquid chromatography is an analytical technique that is useful for separating ions or molecules that are dissolved in a liquid phase. If the sample solution is in contact with a second solid or liquid phase, the different solutes will interact with the other phase to differing degrees due to differences in adsorption, ionic strength, polarity or size. These differences allow the mixture components to be separated from each other by usin g these differences to regulate the transit time of the solutes through a column.Simple liquid chromatography consists of a column with a fritted bottom that holds a stationary phase in residual with a solvent. Typical stationary phases (and their interactions with solutes) are solids (adsorption), ionic groups on a resin (ion-exchange), liquids on an inert solid support (partitioning), and porous inert particles (size exclusion). The mixtur...

Ethics of Cookies Essay -- Technology Computers Internet Essays

Ethics of Cookies ethic 1 plural but singular or plural in whirl the elucidate dealing with what is good and bad and with moral duty and obligation 2 a a set of moral principles or values b a theory or system of moral values <the present-day materialistic ethic c plural but singular or plural in construction the principles of conduct governing an individual or a group <professional ethics d a guiding philosophy HTTP cookie <World-Wide Web A packet of education sent by an HTTP server to a World-Wide Web browser and then sent back by the browser each time it accesses that server. Cookies can soften any arbitrary information the server chooses and are used to maintain state between otherwise stateless HTTP transactions. Typically this is used to authenticate or identify a registered user of a web site without requiring them to sign in again every time they access that site. Other uses are, e.g. maintaining a shop basket of goods you have selected to purchase during a ses sion at a site, site personalisation (presenting different pages to different users), tracking a particular users access to a site. This day and age, it is undisputed that computers are one of the greatest tools for a person to have, and a not having a connection to the internet is a dreadful plan for others. The programs that are used by internet servers are a technology that advance so quickly, that it is difficult for a user to know with what he or she is exactly interacting. For example, if a user were to be browsing through a web site to buy a product, the web site (the server) could build a cookie for the user. The information that a cookie collects is claimed to be harmless by the w... ...may be one answer to this fear of privacy protection but, ultimately it is the responsibleness of the internet users and servers to stay informed of the many different risks of the internet. Bibliography Glassberg, Richy. Dont Fear the Cookie Monster. Mediaweek. 2 Oct. 2000 I Q38. Santa Clara University Expanded Academic Index. The Gale Group. 15 Nov. 2000. <http//w.../purl=rcl_EAIM_0_A66014940&dyn=5xrn_4_0_A66014940?sw_aep=scuweb_cn How Web Servers Cookies exist Your Privacy. Junk Busters. 14 Nov. 2000 <http//www.junkbusters.com/ht/en/cookies.html Lawler, Barbera. Hot button online privacy. Silicon Valley News. 5 Nov. 2000. San Jose Mercury News. 15 Nov 2000 <http//www.mercuryce...news/viewpoints/docs/Soapbox05.htm Persistent Cookie FAQ. Cookie Central. 14 Nov 2000. <http//www.cookiecentral.com/faq.htm